Zeneo® Methotrexate : Treatment for rheumatoid arthritis.
Methotrexate is the standard treatment for rheumatoid arthritis. This molecule is also widely used to treat severe forms of psoriasis.
Rheumatoid arthritis is a chronic, inflammatory disease affecting joints, usually in the hands and feet. It involves episodes of worsening pain, called flair-ups, on a background of usually manageable discomfort.
It is an autoimmune disease, that is, the patient's own immune system make antibodies that attack synovial membranes.
Without treatment, rheumatoid arthritis progresses to new joints and causes the deformation and progressive destruction of the affected joints.
In the United States, rheumatoid arthritis is the third most costly disease, surpassed only by cancer and diabetes (1).
Methotrexate is recommended by the European League Against Rheumatism as the first-line treatment for the disease.
Furthermore, studies (2) have shown that the injection of methotrexate provides better results than the classic oral administration of the treatment. It also reduces adverse effects, resulting in better therapeutic compliance and, in turn, greater benefits for the patient.
(2) Otrexup, 2013
When experiencing rheumatoid arthritis, the patient can self-administer ZENEO® Methotrexate in the thigh.
Another person could also administer the product for the patient, in a ventrogluteal injection.